Centromeres

Also known as... The terms ‘centromere’ and ‘kinetochore’ are often used synonymously but it is best to consider the centromere as the DNA and chromatin on which the kinetochore is assembled and the kinetochore as the protein machine, including centromeric chromatin, which mediates attachment to the spindle. Centromeres are found near the centre of the chromosome on metacentric chromosomes, but they can also be submetacentric, between the middle and an end; acrocentric, close to an end; and telocentric, at an end. Some organisms such as Caenorhabditis elegans are holocentric and assemble centromeric chromatin and kinetochores along the entire chromosome. Delving further you discover that centromeres are eccentric!